Tylophera indica

Tylophera indica [Image]. [2014]. Retrieved from: http://opendata.keystone-foundation.org/tylophora-indica-burm-f-merr

Common name: 
Tylophera 
(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Latin binomial:
Tylophera indica  
(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Parts used:
Leaves
(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Active constituents:
Major constituents of Tylophora include tylophorine and tylophorinine alkaloids

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Actions:

• Anti-inflammatory
• Antihistamine
• Antispasmodic
• Diaphoretic
• Expectorant
• Laxative

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Indications:

• Asthma
• Bronchitis
• Rheumatism 
• Dermatitis

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Contraindications: 

• Known allergy/hypersensitivity to Tylophora.
• Not recommended due to lack of sufficient data.
• Tylophora asthmatica has been reported to have abortifacient properties.

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Cautions:

• Use cautiously in patients with diabetes, congestive heart failure, arrhythmia, hypertension and edema.
• Avoid in patients with serious infections, organ transplantation, major systemic disease or major recent surgery.

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013)

Dosage:

Oral:

• Doses of 250mg once to three times daily, standardized to 0.1% of tylophorine per dose, and doses of 30-60mg twice daily standardized to 0.15% of tylophorine have been reported anecdotally.
• One clinical trial reports using 350mg of Tylophora leaf placed in a capsule and given once daily for 7 days.
• Another clinical trial reports using 0.5mg of alkaloid Tylophora in powder form given once daily to asthmatic patients for 6 days. The patients were instructed to place the powder on their tongues to allow the powder to mix with the saliva and then swallow with a half ounce of water.
• 200mg of Tylophora leaves have been crushed into a powder form and placed in a packet in another clinical trial. The patients were then instructed to take two packets (400mg) daily for six consecutive days.

Dried Herb:

• Anecdotal evidence notes use of Tylophora leaf taken in the amount of 200-400mg dried herb daily.
• A clinical trial reports the use of one Tylophora leaf taken orally daily in the morning for 6 days.
• Another clinical trial by the same author used one leaf of Tylophora daily for up to 12 days in asthmatic patients.

Tincture:

• Tylophora leaf tincture has been given at doses of 1-2mL per day for up to 14 days (anecdotal).
• One clinical trial reports the use of 40mg of alcoholic extract of Tylophora indica daily for 6 days. 

(Gasparyan, McGarry, Basch, Sollars,Ulbricht, 2013) 

References: 

Gasparyan, McGarry, Basch, Sollars,Ulbricht. (2013). Natural standard professional monograph.